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6ZLW

SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit

Summary for 6ZLW
Entry DOI10.2210/pdb6zlw/pdb
EMDB information11276
Descriptor40S ribosomal protein SA, 40S ribosomal protein S5, 40S ribosomal protein S11, ... (37 entities in total)
Functional Keywordstranslational inhibition, sars-cov-2, immune evasion, human ribosome, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains36
Total formula weight1245111.62
Authors
Thoms, M.,Buschauer, R.,Ameismeier, M.,Denk, T.,Kratzat, H.,Mackens-Kiani, T.,Cheng, J.,Berninghausen, O.,Becker, T.,Beckmann, R. (deposition date: 2020-07-01, release date: 2020-07-29, Last modification date: 2020-09-16)
Primary citationThoms, M.,Buschauer, R.,Ameismeier, M.,Koepke, L.,Denk, T.,Hirschenberger, M.,Kratzat, H.,Hayn, M.,Mackens-Kiani, T.,Cheng, J.,Straub, J.H.,Sturzel, C.M.,Frohlich, T.,Berninghausen, O.,Becker, T.,Kirchhoff, F.,Sparrer, K.M.J.,Beckmann, R.
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369:1249-1255, 2020
Cited by
PubMed: 32680882
DOI: 10.1126/science.abc8665
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.6 Å)
Structure validation

217705

數據於2024-03-27公開中

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