6YR3
1.48 Angstrom Resolution Crystal Structure of Transaldolase from Thermoplasma acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Summary for 6YR3
Entry DOI | 10.2210/pdb6yr3/pdb |
Descriptor | Probable transaldolase, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | alpha-beta barrel, conformational selection, domain swapping, transferase, tim barrel, schiff base, large-scale motions, substrate binding, rate-determining product release |
Biological source | Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) |
Total number of polymer chains | 5 |
Total formula weight | 124588.14 |
Authors | Sautner, V.,Tittmann, K. (deposition date: 2020-04-19, release date: 2021-04-28, Last modification date: 2024-01-24) |
Primary citation | Sautner, V.,Lietzow, T.H.,Klaus, M.,Funk, L.M.,Tittmann, K. Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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