6Y97
Structure of full-length CD20 in complex with Obinutuzumab Fab
Summary for 6Y97
Entry DOI | 10.2210/pdb6y97/pdb |
Related | 6Y90 6Y92 |
EMDB information | 10733 |
Descriptor | B-lymphocyte antigen CD20, Obinutuzumab Fab heavy chain, Obinutuzumab Fab light chain (3 entities in total) |
Functional Keywords | cancer immunotherapy, therapeutic antibody, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 62288.59 |
Authors | |
Primary citation | Kumar, A.,Planchais, C.,Fronzes, R.,Mouquet, H.,Reyes, N. Binding mechanisms of therapeutic antibodies to human CD20. Science, 369:793-799, 2020 Cited by PubMed: 32792392DOI: 10.1126/science.abb8008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.33 Å) |
Structure validation
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