6WIV
Structure of human GABA(B) receptor in an inactive state
Summary for 6WIV
Entry DOI | 10.2210/pdb6wiv/pdb |
EMDB information | 21685 |
Descriptor | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | g protein coupled receptor (gpcr), gaba, gaba(b) receptor, class c gpcr, phospholipids, inhibitory neurotransmission., membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 191236.30 |
Authors | Park, J.,Fu, Z.,Frangaj, A.,Liu, J.,Mosyak, L.,Shen, T.,Slavkovich, V.N.,Ray, K.M.,Taura, J.,Cao, B.,Geng, Y.,Zuo, H.,Kou, Y.,Grassucci, R.,Chen, S.,Liu, Z.,Lin, X.,Williams, J.P.,Rice, W.J.,Eng, E.T.,Huang, R.K.,Soni, R.K.,Kloss, B.,Yu, Z.,Javitch, J.A.,Hendrickson, W.A.,Slesinger, P.A.,Quick, M.,Graziano, J.,Yu, H.,Fiehn, O.,Clarke, O.B.,Frank, J.,Fan, Q.R. (deposition date: 2020-04-10, release date: 2020-07-01, Last modification date: 2020-08-26) |
Primary citation | Park, J.,Fu, Z.,Frangaj, A.,Liu, J.,Mosyak, L.,Shen, T.,Slavkovich, V.N.,Ray, K.M.,Taura, J.,Cao, B.,Geng, Y.,Zuo, H.,Kou, Y.,Grassucci, R.,Chen, S.,Liu, Z.,Lin, X.,Williams, J.P.,Rice, W.J.,Eng, E.T.,Huang, R.K.,Soni, R.K.,Kloss, B.,Yu, Z.,Javitch, J.A.,Hendrickson, W.A.,Slesinger, P.A.,Quick, M.,Graziano, J.,Yu, H.,Fiehn, O.,Clarke, O.B.,Frank, J.,Fan, Q.R. Structure of human GABABreceptor in an inactive state. Nature, 584:304-309, 2020 Cited by PubMed: 32581365DOI: 10.1038/s41586-020-2452-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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