6V64
Crystal structure of human thrombin bound to ppack with tryptophans replaced by 5-F-tryptophan
Summary for 6V64
Entry DOI | 10.2210/pdb6v64/pdb |
Related | 1ppb |
Descriptor | Thrombin light chain, Thrombin heavy chain, SODIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 33960.07 |
Authors | Ruben, E.A.,Chen, Z.,Di Cera, E. (deposition date: 2019-12-04, release date: 2020-05-13, Last modification date: 2023-10-11) |
Primary citation | Ruben, E.A.,Gandhi, P.S.,Chen, Z.,Koester, S.K.,DeKoster, G.T.,Frieden, C.,Di Cera, E. 19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2. J.Biol.Chem., 295:8227-8235, 2020 Cited by PubMed: 32358061DOI: 10.1074/jbc.RA120.013419 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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