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6UMU

Human apo PD-1 triple mutant

Summary for 6UMU
Entry DOI10.2210/pdb6umu/pdb
DescriptorProgrammed cell death protein 1, CHLORIDE ION (3 entities in total)
Functional Keywordspd-1, immune checkpoint, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight14584.11
Authors
Tang, S.,Kim, P.S. (deposition date: 2019-10-10, release date: 2019-11-27, Last modification date: 2023-10-11)
Primary citationTang, S.,Kim, P.S.
A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116:24500-24506, 2019
Cited by
PubMed: 31727844
DOI: 10.1073/pnas.1916916116
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.183 Å)
Structure validation

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