7LUL

Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide

Replaces:  6UBG

Summary for 7LUL

• Entry DOI: 10.2210/pdb7lul/pdb
• Related: 1N7T 6Q0M 6Q0N 6Q0U 6UBH
• Descriptor: Erbin, peptide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total)
• Functional Keywords: phage display, directed evolution, -2 position, specificity, phage library, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 12043.58

Authors

Singer, A.U.,Teyra, J.,McLaughlin, M.,Ernst, A.,Sicheri, F.,Sidhu, S.S. (deposition date: 2021-02-22, release date: 2021-07-28, Last modification date: 2024-04-03)

• Primary citation: Teyra, J.,McLaughlin, M.,Singer, A.,Kelil, A.,Ernst, A.,Sicheri, F.,Sidhu, S.S.; Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.; J.Mol.Biol., 433:167115-167115, 2021; PubMed: 34171344; DOI: 10.1016/j.jmb.2021.167115

Experimental method

X-RAY DIFFRACTION (1.65 Å)