6UAN

B-Raf:14-3-3 complex

Summary for 6UAN

Entry DOI	10.2210/pdb6uan/pdb
EMDB information	20708
Descriptor	14-3-3 zeta, Serine/threonine-protein kinase B-raf (2 entities in total)
Functional Keywords	complex kinase, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	225780.87
Authors	Kondo, Y.,Ognjenovic, J.,Banerjee, S.,Karandur, D.,Merk, A.,Kulhanek, K.,Wong, K.,Roose, J.P.,Subramaniam, S.,Kuriyan, J. (deposition date: 2019-09-11, release date: 2019-09-25, Last modification date: 2019-12-18)
Primary citation	Kondo, Y.,Ognjenovic, J.,Banerjee, S.,Karandur, D.,Merk, A.,Kulhanek, K.,Wong, K.,Roose, J.P.,Subramaniam, S.,Kuriyan, J. Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Science, 366:109-115, 2019 Cited by PubMed: 31604311 DOI: 10.1126/science.aay0543 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation