6U69

Crystal structure of Yck2 from Candida albicans, apoenzyme

6U69 の概要

• エントリーDOI: 10.2210/pdb6u69/pdb
• 分子名称: Serine/threonine protein kinase, SULFATE ION, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: casein kinase 1, yck2, kinase, structural genomics, center for structural genomics of infectious diseases, niaid, national institute of allergy and infectious diseases, csgid, transferase
• 由来する生物種: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35620.86

構造登録者

Stogios, P.J.,Evdokimova, E.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2019-08-29, 公開日: 2019-10-09, 最終更新日: 2023-10-11)

• 主引用文献: Caplan, T.,Lorente-Macias, A.,Stogios, P.J.,Evdokimova, E.,Hyde, S.,Wellington, M.A.,Liston, S.,Iyer, K.R.,Puumala, E.,Shekhar-Guturja, T.,Robbins, N.,Savchenko, A.,Krysan, D.J.,Whitesell, L.,Zuercher, W.J.,Cowen, L.E.; Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2.; Cell Chem Biol, 27:269-282.e5, 2020; PubMed: 31924499; DOI: 10.1016/j.chembiol.2019.12.008

実験手法

X-RAY DIFFRACTION (2.61 Å)