6TED
Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1
Summary for 6TED
Entry DOI | 10.2210/pdb6ted/pdb |
EMDB information | 10480 |
Descriptor | DNA-directed RNA polymerase subunit, Uncharacterized protein, Transcription elongation factor SPT6, ... (26 entities in total) |
Functional Keywords | polymerase, elongation complex, rna, dna, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 24 |
Total formula weight | 1351868.46 |
Authors | |
Primary citation | Vos, S.M.,Farnung, L.,Linden, A.,Urlaub, H.,Cramer, P. Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27:668-677, 2020 Cited by PubMed: 32541898DOI: 10.1038/s41594-020-0437-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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