6T1Z

LmrP from L. lactis, in an outward-open conformation, bound to Hoechst 33342

6T1Z の概要

• エントリーDOI: 10.2210/pdb6t1z/pdb
• 分子名称: LmrP integral membrane protein, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: transmembrane multidrug transporter, transport protein
• 由来する生物種: Lactococcus lactis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48026.93

構造登録者

Hutchin, A.,Debruycker, V.,Masureel, M.,Legrand, P.,Remaut, H.,Govaerts, C. (登録日: 2019-10-07, 公開日: 2020-07-29, 最終更新日: 2024-05-01)

• 主引用文献: Debruycker, V.,Hutchin, A.,Masureel, M.,Ficici, E.,Martens, C.,Legrand, P.,Stein, R.A.,Mchaourab, H.S.,Faraldo-Gomez, J.D.,Remaut, H.,Govaerts, C.; An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity.; Nat.Struct.Mol.Biol., 27:829-835, 2020; PubMed: 32719456; DOI: 10.1038/s41594-020-0464-y

実験手法

X-RAY DIFFRACTION (2.9 Å)