6SQF
Crystal structure of CREBBP bromodomain complexed with LB32A
Summary for 6SQF
Entry DOI | 10.2210/pdb6sqf/pdb |
Descriptor | CREB-binding protein, ~{N}-[3-[[5-ethanoyl-2-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]phenyl]carbamoyl]-5-(1-methylpyrazol-3-yl)phenyl]furan-2-carboxamide (3 entities in total) |
Functional Keywords | inhibitor, complex, crebbp, bromodomain, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14792.96 |
Authors | Bedi, R.K.,Laul, E.,Nevado, C.,Caflisch, A. (deposition date: 2019-09-03, release date: 2020-09-30, Last modification date: 2024-05-15) |
Primary citation | Bedi, R.K.,Laul, E.,Nevado, C.,Caflisch, A. Crystal structure of CREBBP bromodomain complexed with LB32A To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.006 Å) |
Structure validation
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