6S0B

Crystal Structure of Properdin in complex with the CTC domain of C3/C3b

Summary for 6S0B

Entry DOI	10.2210/pdb6s0b/pdb
Descriptor	Properdin, Complement C3, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, ... (7 entities in total)
Functional Keywords	innate immunity, complement, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	56213.90
Authors	van den Bos, R.M.,Pearce, N.M.,Gros, P. (deposition date: 2019-06-14, release date: 2019-09-04, Last modification date: 2020-07-29)
Primary citation	van den Bos, R.M.,Pearce, N.M.,Granneman, J.,Brondijk, T.H.C.,Gros, P. Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b. Front Immunol, 10:2097-2097, 2019 Cited by PubMed: 31552043 DOI: 10.3389/fimmu.2019.02097 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.312 Å)

Structure validation