6RMM

Crystal structure of TOPBP1 BRCT4,5 in complex with a 53BP1 phosphopeptide

Summary for 6RMM

• Entry DOI: 10.2210/pdb6rmm/pdb
• Descriptor: DNA topoisomerase 2-binding protein 1, 53BP1 (2 entities in total)
• Functional Keywords: brct domain phosphopeptide recognition, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 89291.41

Authors

Day, M.,Oliver, A.W.,Pearl, L.H. (deposition date: 2019-05-07, release date: 2019-06-12, Last modification date: 2024-01-24)

• Primary citation: Bigot, N.,Day, M.,Baldock, R.A.,Watts, F.Z.,Oliver, A.W.,Pearl, L.H.; Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.; Elife, 8:-, 2019; PubMed: 31135337; DOI: 10.7554/eLife.44353

Experimental method

X-RAY DIFFRACTION (3.53 Å)