6R9P

Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAUUAA RNA

Summary for 6R9P

Related6R9I
DescriptorPAN2-PAN3 deadenylation complex catalytic subunit PAN2, AAUUAA RNA (2 entities in total)
Functional Keywordsdedd rnase, deadenylase, pseudoubiquitin hydrolase, hydrolase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Total number of polymer chains2
Total molecular weight79660.3
Authors
Tang, T.T.L.,Stowell, J.A.W.,Hill, C.H.,Passmore, L.A. (deposition date: 2019-04-03, release date: 2019-05-22, Last modification date: 2019-08-21)
Primary citation
Tang, T.T.L.,Stowell, J.A.W.,Hill, C.H.,Passmore, L.A.
The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26:433-442, 2019
PubMed: 31110294 (PDB entries with the same primary citation)
DOI: 10.1038/s41594-019-0227-9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.98 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.310170 4.6% 2.8% 0.42MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution