6R4Y
Crystal structure of holo PPEP-1(E143A/Y178F) in complex with product peptide Ac-EVNP-CO2 (substrate peptide: Ac-EVNPAVP-CONH2)
Summary for 6R4Y
| Entry DOI | 10.2210/pdb6r4y/pdb |
| Descriptor | Pro-Pro endopeptidase, ACE-GLU-VAL-ASN-PRO, ZINC ION, ... (4 entities in total) |
| Functional Keywords | pro-pro endopeptidase 1, zinc metallopeptidase, clostridium difficile, virulence factor, hydrolase |
| Biological source | Peptoclostridium difficile More |
| Total number of polymer chains | 4 |
| Total formula weight | 44917.14 |
| Authors | Pichlo, C.,Baumann, U. (deposition date: 2019-03-24, release date: 2019-06-12, Last modification date: 2024-01-24) |
| Primary citation | Pichlo, C.,Juetten, L.,Wojtalla, F.,Schacherl, M.,Diaz, D.,Baumann, U. Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1. J.Biol.Chem., 294:11525-11535, 2019 Cited by PubMed: 31182482DOI: 10.1074/jbc.RA119.009029 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.452 Å) |
Structure validation
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