6QZK

Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA

Summary for 6QZK

• Entry DOI: 10.2210/pdb6qzk/pdb
• Descriptor: Clostridium butyricum Argonaute, siDNA guide (5'-D(P*CP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), ... (6 entities in total)
• Functional Keywords: argonaute, pago, ago, cbago, hydrolase
• Biological source: Clostridium butyricum; More
• Total number of polymer chains: 3
• Total formula weight: 98338.40

Authors

Swarts, D.C.,Jinek, M.,Hegge, J.W.,Van der Oost, J. (deposition date: 2019-03-11, release date: 2019-04-24, Last modification date: 2024-01-24)

• Primary citation: Hegge, J.W.,Swarts, D.C.,Chandradoss, S.D.,Cui, T.J.,Kneppers, J.,Jinek, M.,Joo, C.,van der Oost, J.; DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.; Nucleic Acids Res., 47:5809-5821, 2019; PubMed: 31069393; DOI: 10.1093/nar/gkz306

Experimental method

X-RAY DIFFRACTION (3.548 Å)