6QX9

Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).

This is a non-PDB format compatible entry.

Summary for 6QX9

• Entry DOI: 10.2210/pdb6qx9/pdb
• Related: 6QW6
• EMDB information: 4658 4665
• Descriptor: U1 snRNA, U4/U6 small nuclear ribonucleoprotein Prp31, Small nuclear ribonucleoprotein Sm D1, ... (54 entities in total)
• Functional Keywords: rnp complex, splicing, rna, protein, spliceosome
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 71
• Total formula weight: 2871622.27

Authors

Charenton, C.,Wilkinson, M.E.,Nagai, K. (deposition date: 2019-03-07, release date: 2019-04-17, Last modification date: 2020-10-07)

• Primary citation: Charenton, C.,Wilkinson, M.E.,Nagai, K.; Mechanism of 5' splice site transfer for human spliceosome activation.; Science, 364:362-367, 2019; PubMed: 30975767; DOI: 10.1126/science.aax3289

Experimental method

ELECTRON MICROSCOPY (3.28 Å)