6QJQ

Cryo-EM structure of heparin-induced 2N3R tau filaments

Summary for 6QJQ

Entry DOI	10.2210/pdb6qjq/pdb
EMDB information	4566
Descriptor	Microtubule-associated protein tau (1 entity in total)
Functional Keywords	recombinant tau protein, heparin, filament, cross-beta structure, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	17828.87
Authors	Zhang, W.,Falcon, B.,Murzin, A.G.,Fan, J.,Crowther, R.A.,Goedert, M.,Scheres, S.H.W. (deposition date: 2019-01-24, release date: 2019-02-20)
Primary citation	Zhang, W.,Falcon, B.,Murzin, A.G.,Fan, J.,Crowther, R.A.,Goedert, M.,Scheres, S.H. Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8:-, 2019 Cited by PubMed: 30720432 DOI: 10.7554/eLife.43584 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation