6QEB

Assessment of a large enzyme-drug complex by proton-detected solid-state NMR without deuteration

Summary for 6QEB

DescriptorCarbonic anhydrase 2, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE (3 entities in total)
Functional Keywordshcaii solid state nmr acetazolamide, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight29576.72
Authors
Vasa, S.K. (deposition date: 2019-01-07, release date: 2019-02-06)
Primary citation
Vasa, S.K.,Singh, H.,Grohe, K.,Linser, R.
Assessment of a large enzyme-drug complex by proton-detected solid-state NMR without deuteration.
Angew. Chem. Int. Ed. Engl., 2019
PubMed: 30688395 (PDB entries with the same primary citation)
DOI: 10.1002/anie.201811714
MImport into Mendeley
Experimental method
SOLID-STATE NMR
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers3 3.4% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 6qeb
no rotation
Molmil generated image of 6qeb
rotated about x axis by 90°
Molmil generated image of 6qeb
rotated about y axis by 90°
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan