6QA2
R80A MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Summary for 6QA2
| Entry DOI | 10.2210/pdb6qa2/pdb |
| Descriptor | Nucleoside diphosphate kinase, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, ... (4 entities in total) |
| Functional Keywords | remodeling, open and closed binding site, transferase |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) |
| Total number of polymer chains | 6 |
| Total formula weight | 88097.30 |
| Authors | Dautant, A.,Henri, J.,Wales, T.E.,Meyer, P.,Engen, J.R.,Georgescauld, F. (deposition date: 2018-12-18, release date: 2019-02-27, Last modification date: 2024-01-24) |
| Primary citation | Dautant, A.,Henri, J.,Wales, T.E.,Meyer, P.,Engen, J.R.,Georgescauld, F. Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange. Biochemistry, 58:1440-1449, 2019 Cited by PubMed: 30785730DOI: 10.1021/acs.biochem.8b01308 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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