6PPA

Crystal structure of the unliganded bromodomain of human BRD7

Summary for 6PPA

Entry DOI	10.2210/pdb6ppa/pdb
Descriptor	Bromodomain-containing protein 7, PHOSPHATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	brd7, pbaf, celtix-1, mswi/snf, bp75, gene regulation
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	14613.75
Authors	Chan, A.,Karim, M.R.,Zhu, J.,Schonbrunn, E. (deposition date: 2019-07-05, release date: 2020-03-11, Last modification date: 2023-10-11)
Primary citation	Karim, R.M.,Chan, A.,Zhu, J.Y.,Schonbrunn, E. Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains. J.Med.Chem., 63:3227-3237, 2020 Cited by PubMed: 32091206 DOI: 10.1021/acs.jmedchem.9b01980 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation