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6PA7

The cryo-EM structure of the human DNMT3A2-DNMT3B3 complex bound to nucleosome.

Summary for 6PA7
Entry DOI10.2210/pdb6pa7/pdb
EMDB information20281 21689
DescriptorHistone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
Functional Keywordsmethyltransferase, complex, transferase, transferase-dna complex, transferase/dna
Biological sourceXenopus laevis (African clawed frog)
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Total number of polymer chains14
Total formula weight541073.19
Authors
Xu, T.H.,Liu, M.,Zhou, X.E.,Liang, G.,Zhao, G.,Xu, H.E.,Melcher, K.,Jones, P.A. (deposition date: 2019-06-11, release date: 2020-06-17, Last modification date: 2024-03-20)
Primary citationXu, T.H.,Liu, M.,Zhou, X.E.,Liang, G.,Zhao, G.,Xu, H.E.,Melcher, K.,Jones, P.A.
Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
Nature, 586:151-155, 2020
Cited by
PubMed: 32968275
DOI: 10.1038/s41586-020-2747-1
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.94 Å)
Structure validation

217705

数据于2024-03-27公开中

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