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6OVQ

Crystal structure of mithramycin 3-side chain keto-reductase MtmW

Summary for 6OVQ
Entry DOI10.2210/pdb6ovq/pdb
DescriptorPutative Side chain reductase, GLYCEROL (3 entities in total)
Functional Keywordsnatural product, biosynthesis, aureolic acid, reductase, oxidoreductase
Biological sourceStreptomyces argillaceus
Total number of polymer chains2
Total formula weight72858.89
Authors
Hou, C.,Yu, X.,Rohr, J.,Tsodikov, O.V. (deposition date: 2019-05-08, release date: 2019-11-27, Last modification date: 2023-10-11)
Primary citationWheeler, R.,Yu, X.,Hou, C.,Mitra, P.,Chen, J.M.,Herkules, F.,Ivanov, D.N.,Tsodikov, O.V.,Rohr, J.
Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59:826-832, 2020
Cited by
PubMed: 31702856
DOI: 10.1002/anie.201910241
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

218853

数据于2024-04-24公开中

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