6OH8

Crystal structure of (E)-biformene synthase LrdC from Streptomyces sp. strain K155 in the dimeric form

Replaces:  5A0I

Summary for 6OH8

• Entry DOI: 10.2210/pdb6oh8/pdb
• Descriptor: Labdane-related diterpene synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... (4 entities in total)
• Functional Keywords: bioactive natural products, biformene, diterpene synthase, labdatriene, lyase
• Biological source: Streptomyces sp.
• Total number of polymer chains: 2
• Total formula weight: 75102.91

Authors

Centeno-Leija, S.,Serrano-Posada, H. (deposition date: 2019-04-04, release date: 2019-04-17, Last modification date: 2024-04-03)

• Primary citation: Centeno-Leija, S.,Tapia-Cabrera, S.,Guzman-Trampe, S.,Esquivel, B.,Esturau-Escofet, N.,Tierrafria, V.H.,Rodriguez-Sanoja, R.,Zarate-Romero, A.,Stojanoff, V.,Rudino-Pinera, E.,Sanchez, S.,Serrano-Posada, H.; The structure of (E)-biformene synthase provides insights into the biosynthesis of bacterial bicyclic labdane-related diterpenoids.; J.Struct.Biol., 207:29-39, 2019; PubMed: 30981884; DOI: 10.1016/j.jsb.2019.04.010

Experimental method

X-RAY DIFFRACTION (2.17 Å)