6OGX

Ternary complex of OX40R (TNFRSF4) bound to Fab1 and Fab2

Summary for 6OGX

• Entry DOI: 10.2210/pdb6ogx/pdb
• Descriptor: Fab 1 Heavy Chain, Fab1 Light Chain, Tumor necrosis factor receptor superfamily member 4, ... (7 entities in total)
• Functional Keywords: tnfrsf4, cd134, ox40r, fab, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 112763.66

Authors

Ultsch, M.H.,Boenig, G.,Harris, S.F. (deposition date: 2019-04-03, release date: 2019-07-10, Last modification date: 2020-07-29)

• Primary citation: Yang, Y.,Yeh, S.H.,Madireddi, S.,Matochko, W.L.,Gu, C.,Pacheco Sanchez, P.,Ultsch, M.,De Leon Boenig, G.,Harris, S.F.,Leonard, B.,Scales, S.J.,Zhu, J.W.,Christensen, E.,Hang, J.Q.,Brezski, R.J.,Marsters, S.,Ashkenazi, A.,Sukumaran, S.,Chiu, H.,Cubas, R.,Kim, J.M.,Lazar, G.A.; Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.; Mabs, 11:996-1011, 2019; PubMed: 31156033; DOI: 10.1080/19420862.2019.1625662

Experimental method

X-RAY DIFFRACTION (2.77 Å)