6OF8

Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CamKII-alpha hub domain

Summary for 6OF8

Entry DOI	10.2210/pdb6of8/pdb
Descriptor	Calcium/calmodulin-dependent protein kinase type II subunit alpha, POTASSIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	camkii hub domain, signaling protein, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	7
Total formula weight	109332.82
Authors	McSpadden, E.D.,Chi, C.C.,Gee, C.L.,Kuriyan, J. (deposition date: 2019-03-28, release date: 2019-04-17, Last modification date: 2023-10-11)
Primary citation	McSpadden, E.D.,Xia, Z.,Chi, C.C.,Susa, A.C.,Shah, N.H.,Gee, C.L.,Williams, E.R.,Kuriyan, J. Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II. Protein Sci., 28:1071-1082, 2019 Cited by PubMed: 30942928 DOI: 10.1002/pro.3614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation