6O9L
Human holo-PIC in the closed state
Summary for 6O9L
| Entry DOI | 10.2210/pdb6o9l/pdb |
| EMDB information | 3307 |
| Descriptor | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (36 entities in total) |
| Functional Keywords | transcription initiation, molecular dynamics, gene regulation, community network analysis, global protein dynamics, rna polymerase, transcription-dna complex, transcription/dna |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 33 |
| Total formula weight | 1379416.00 |
| Authors | Yan, C.L.,Dodd, T.,He, Y.,Tainer, J.A.,Tsutakawa, S.E.,Ivanov, I. (deposition date: 2019-03-14, release date: 2019-05-29, Last modification date: 2024-03-13) |
| Primary citation | Yan, C.,Dodd, T.,He, Y.,Tainer, J.A.,Tsutakawa, S.E.,Ivanov, I. Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat.Struct.Mol.Biol., 26:397-406, 2019 Cited by PubMed: 31110295DOI: 10.1038/s41594-019-0220-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (7.2 Å) |
Structure validation
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