6O7G
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
Summary for 6O7G
| Entry DOI | 10.2210/pdb6o7g/pdb |
| NMR Information | BMRB: 30585 |
| Descriptor | Histone-lysine N-methyltransferase 2D, Histone H4, ZINC ION (3 entities in total) |
| Functional Keywords | mll4, phd finger, h4k16ac, mof, acetylation, histone, chromatin, transcription |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 8635.49 |
| Authors | Zhang, Y.,Kutateladze, T.G. (deposition date: 2019-03-07, release date: 2019-05-22, Last modification date: 2023-11-15) |
| Primary citation | Zhang, Y.,Jang, Y.,Lee, J.E.,Ahn, J.,Xu, L.,Holden, M.R.,Cornett, E.M.,Krajewski, K.,Klein, B.J.,Wang, S.P.,Dou, Y.,Roeder, R.G.,Strahl, B.D.,Rothbart, S.B.,Shi, X.,Ge, K.,Kutateladze, T.G. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nat Commun, 10:2314-2314, 2019 Cited by PubMed: 31127101DOI: 10.1038/s41467-019-10324-8 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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