6O48

Wild-type HIV-1 protease in complex with a substrate analog CA-p2

Summary for 6O48

• Entry DOI: 10.2210/pdb6o48/pdb
• Related: 1A8K 6O5X
• Related PRD ID: PRD_000349
• Descriptor: HIV-1 protease, SODIUM ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: hiv protease, hydrolase, viral protein
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 22546.42

Authors

Wang, Y.-F.,Liu, F.,Weber, I.T. (deposition date: 2019-02-28, release date: 2019-06-19, Last modification date: 2023-10-11)

• Primary citation: Agniswamy, J.,Kneller, D.W.,Brothers, R.,Wang, Y.F.,Harrison, R.W.,Weber, I.T.; Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues.; Acs Omega, 4:8707-8719, 2019; PubMed: 31172041; DOI: 10.1021/acsomega.9b00683

Experimental method

X-RAY DIFFRACTION (1.46 Å)