6NZZ
LRRC8A-DCPIB in MSP1E3D1 nanodisc expanded state
Summary for 6NZZ
Entry DOI | 10.2210/pdb6nzz/pdb |
Related | 6NZW |
EMDB information | 0562 0563 |
Descriptor | Volume-regulated anion channel subunit LRRC8A, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}butanoic acid (3 entities in total) |
Functional Keywords | ion channel, volume-regulation, membrane protein |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 6 |
Total formula weight | 585996.10 |
Authors | Kern, D.M.,Hite, R.K.,Brohawn, S.G. (deposition date: 2019-02-14, release date: 2019-02-27, Last modification date: 2019-12-18) |
Primary citation | Kern, D.M.,Oh, S.,Hite, R.K.,Brohawn, S.G. Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs. Elife, 8:-, 2019 Cited by PubMed: 30775971DOI: 10.7554/eLife.42636 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.32 Å) |
Structure validation
Download full validation report