Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2

Summary for 6NZ0

EMDB information0553 0621 0622 0623 0624
DescriptorDyslexia-associated protein KIAA0319-like protein, Capsid protein VP1, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsaav, aavr, receptor, coreceptor, virus, kiaa0319l, pkd, parvovirus
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight113939.14
Meyer, N.L.,Xie, Q.,Davulcu, O.,Yoshioka, C.,Chapman, M.S. (deposition date: 2019-02-12, release date: 2019-06-12, Last modification date: 2019-06-19)
Primary citation
Meyer, N.L.,Hu, G.,Davulcu, O.,Xie, Q.,Noble, A.J.,Yoshioka, C.,Gingerich, D.S.,Trzynka, A.,David, L.,Stagg, S.M.,Chapman, M.S.
Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR.
Elife, 8:-, 2019
PubMed: 31115336 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.44707
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers9 0.3% 2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures