6NTZ

Crystal structure of E. coli PBP5-meropenem

6NTZ の概要

分子名称D-alanyl-D-alanine carboxypeptidase, (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid (3 entities in total)
機能のキーワードcarboxypeptidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase-antibiotic complex, hydrolase/antibiotic
由来する生物種Escherichia coli
ポリマー鎖数1
分子量合計44879.3
構造登録者
Caveney, N.A.,Strynadka, N.C.J.,Caballero, G.,Worrall, L.J. (登録日: 2019-01-30, 公開日: 2019-03-20)
主引用文献
Caveney, N.A.,Caballero, G.,Voedts, H.,Niciforovic, A.,Worrall, L.J.,Vuckovic, M.,Fonvielle, M.,Hugonnet, J.,Arthur, M.,Strynadka, N.C.J.
Structural insight into YcbB mediated beta-lactam resistance in Escherichia coli
Nat Commun, 2019
実験手法
X-RAY DIFFRACTION (2.2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2627 0.8% 2.3% 3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 6ntz
回転なし
Molmil generated image of 6ntz
x軸(左右方向)周りに90°回転
Molmil generated image of 6ntz
y軸(上下方向)周りに90°回転