6NT8
Cryo-EM structure of full-length chicken STING in the cGAMP-bound tetrameric state
Summary for 6NT8
| Entry DOI | 10.2210/pdb6nt8/pdb |
| EMDB information | 0505 |
| Descriptor | Stimulator of interferon genes protein, cGAMP (2 entities in total) |
| Functional Keywords | er, membrane, adaptor, immune system |
| Biological source | Gallus gallus (Chicken) |
| Total number of polymer chains | 4 |
| Total formula weight | 178177.10 |
| Authors | Shang, G.,Zhang, C.,Chen, Z.J.,Bai, X.,Zhang, X. (deposition date: 2019-01-28, release date: 2019-03-06, Last modification date: 2024-03-20) |
| Primary citation | Shang, G.,Zhang, C.,Chen, Z.J.,Bai, X.C.,Zhang, X. Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567:389-393, 2019 Cited by PubMed: 30842659DOI: 10.1038/s41586-019-0998-5 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (6.5 Å) |
Structure validation
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