6NSG

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin G186V/L194P mutant in complex with 6'-SLNLN

6NSG の概要

• エントリーDOI: 10.2210/pdb6nsg/pdb
• 分子名称: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: viral protein
• 由来する生物種: Influenza A virus (A/Brisbane/10/2007(H3N2)); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59175.75

構造登録者

Wu, N.C.,Wilson, I.A. (登録日: 2019-01-24, 公開日: 2019-04-24, 最終更新日: 2023-10-11)

• 主引用文献: Wu, N.C.,Lv, H.,Thompson, A.J.,Wu, D.C.,Ng, W.W.S.,Kadam, R.U.,Lin, C.W.,Nycholat, C.M.,McBride, R.,Liang, W.,Paulson, J.C.,Mok, C.K.P.,Wilson, I.A.; Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility.; Cell Host Microbe, 25:836-, 2019; PubMed: 31151913; DOI: 10.1016/j.chom.2019.04.013

実験手法

X-RAY DIFFRACTION (2.4 Å)