6NSG

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin G186V/L194P mutant in complex with 6'-SLNLN

Summary for 6NSG

DescriptorHemagglutinin HA1 chain, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ... (8 entities in total)
Functional Keywordsviral protein
Biological sourceInfluenza A virus (A/Brisbane/10/2007(H3N2))
Total number of polymer chains2
Total molecular weight59319.87
Authors
Wu, N.C.,Wilson, I.A. (deposition date: 2019-01-24, release date: 2019-04-24)
Primary citation
Wu, N.C.,Lv, H.,Thompson, A.J.,Wu, D.C.,Ng, W.W.S.,Kadam, R.U.,Lin, C.W.,Nycholat, C.M.,McBride, R.,Liang, W.,Paulson, J.C.,Mok, C.K.P.,Wilson, I.A.
Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23010 3.5% 9.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6nsg
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Molmil generated image of 6nsg
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Molmil generated image of 6nsg
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More Biological unit images

Molmil generated image of 6nsg
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Molmil generated image of 6nsg
rotated about x axis by 90°
Molmil generated image of 6nsg
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6nsg.pdb1.gz [512.34 KB])