6NSG

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin G186V/L194P mutant in complex with 6'-SLNLN

Summary for 6NSG

Entry DOI	10.2210/pdb6nsg/pdb
Descriptor	Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	viral protein
Biological source	Influenza A virus (A/Brisbane/10/2007(H3N2)) More
Total number of polymer chains	2
Total formula weight	59175.75
Authors	Wu, N.C.,Wilson, I.A. (deposition date: 2019-01-24, release date: 2019-04-24, Last modification date: 2023-10-11)
Primary citation	Wu, N.C.,Lv, H.,Thompson, A.J.,Wu, D.C.,Ng, W.W.S.,Kadam, R.U.,Lin, C.W.,Nycholat, C.M.,McBride, R.,Liang, W.,Paulson, J.C.,Mok, C.K.P.,Wilson, I.A. Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility. Cell Host Microbe, 25:836-, 2019 Cited by PubMed: 31151913 DOI: 10.1016/j.chom.2019.04.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation