6NQM
Crystal structure of Human LSD1
Summary for 6NQM
| Entry DOI | 10.2210/pdb6nqm/pdb |
| Descriptor | Lysine-specific histone demethylase 1A, FLAVIN-ADENINE DINUCLEOTIDE (2 entities in total) |
| Functional Keywords | lysine-specific histone demethylase, cofactor, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 74091.39 |
| Authors | Tan, A.H.Y.,Tu, W.,McCuaig, R.,Donovan, T.,Tsimbalyuk, S.,Forwood, J.K.,Rao, S. (deposition date: 2019-01-21, release date: 2019-02-13, Last modification date: 2023-10-11) |
| Primary citation | Tan, A.H.Y.,Tu, W.,McCuaig, R.,Hardy, K.,Donovan, T.,Tsimbalyuk, S.,Forwood, J.K.,Rao, S. Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer. Front Immunol, 10:1351-1351, 2019 Cited by PubMed: 31249575DOI: 10.3389/fimmu.2019.01351 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report
