6NQA

Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 1-to-1 complex

Summary for 6NQA

Entry DOI	10.2210/pdb6nqa/pdb
EMDB information	0468 0480 9384
Descriptor	601 DNA Strand 1, 601 DNA Strand 2, Histone H4, ... (9 entities in total)
Functional Keywords	ubiquitin, nucleosome, methyltransferase, structural protein-transferase-dna complex, structural protein/transferase/dna
Biological source	synthetic construct More
Total number of polymer chains	12
Total formula weight	254982.29
Authors	Worden, E.J.,Hoffmann, N.A.,Wolberger, C. (deposition date: 2019-01-19, release date: 2019-02-20, Last modification date: 2020-01-08)
Primary citation	Worden, E.J.,Hoffmann, N.A.,Hicks, C.W.,Wolberger, C. Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L. Cell, 176:1490-1501.e12, 2019 Cited by PubMed: 30765112 DOI: 10.1016/j.cell.2019.02.002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.54 Å)

Structure validation