6NN6

Structure of Dot1L-H2BK120ub nucleosome complex

Summary for 6NN6

Entry DOI	10.2210/pdb6nn6/pdb
EMDB information	0458 0459 0460
Descriptor	Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total)
Functional Keywords	chromatin, structural biology, single particle, cryo-em, histone methyltransferase, nucleosome, dot1l, gene regulation
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	12
Total formula weight	254261.76
Authors	Anderson, C.J.,Baird, M.R.,Hsu, A.,Barbour, E.H.,Koyama, Y.,Borgnia, M.J.,McGinty, R.K. (deposition date: 2019-01-14, release date: 2019-02-13, Last modification date: 2024-03-20)
Primary citation	Anderson, C.J.,Baird, M.R.,Hsu, A.,Barbour, E.H.,Koyama, Y.,Borgnia, M.J.,McGinty, R.K. Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase. Cell Rep, 26:1681-1690.e5, 2019 Cited by PubMed: 30759380 DOI: 10.1016/j.celrep.2019.01.058 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation