FAD-dependent monooxygenase TropB from T. stipitatus substrate complex

Summary for 6NET

DescriptorFAD-dependent monooxygenase tropB, 2,4-dihydroxy-3,6-dimethylbenzaldehyde, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total)
Functional Keywordsoxidative dearomatization, flavoprotein
Biological sourceTalaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum)
Total number of polymer chains2
Total molecular weight102116.27
Primary citation
Rodriguez Benitez, A.,Tweedy, S.E.,Baker Dockrey, S.A.,Lukowski, A.L.,Wymore, T.,Khare, D.,Brooks 3rd, C.L.,Palfey, B.A.,Smith, J.L.,Narayan, A.R.H.
Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9:3633-3640, 2019
PubMed: 31346489 (PDB entries with the same primary citation)
DOI: 10.1021/acscatal.8b04575
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23550 2.0% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution