6N5W

Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains

Summary for 6N5W

Entry DOI	10.2210/pdb6n5w/pdb
Descriptor	Potassium voltage-gated channel subfamily KQT member 4, Calmodulin-1, CALCIUM ION, ... (5 entities in total)
Functional Keywords	ion channel, calmodulin, kcnq4 peptides, complex, metal binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	23216.27
Authors	Taylor, A.B.,Archer, C.R.,Shapiro, M.S. (deposition date: 2018-11-22, release date: 2019-03-13, Last modification date: 2023-10-11)
Primary citation	Archer, C.R.,Enslow, B.T.,Taylor, A.B.,De la Rosa, V.,Bhattacharya, A.,Shapiro, M.S. A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+channels. J. Biol. Chem., 294:6094-6112, 2019 Cited by PubMed: 30808708 DOI: 10.1074/jbc.RA118.006857 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation