6N3P

Crosslinked AcpP=FabZ complex from E. coli Type II FAS

Summary for 6N3P

Entry DOI	10.2210/pdb6n3p/pdb
Descriptor	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, Acyl carrier protein, N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(3-{[(1Z)-pent-1-en-1-yl]sulfonyl}propyl)-beta-alaninamide, ... (4 entities in total)
Functional Keywords	fatty acid biosynthsis, fas, dehydratase, crosslinking, acyl carrier protein, acp, fabz, acpp, e. coli, biosynthetic protein
Biological source	Escherichia coli More
Total number of polymer chains	12
Total formula weight	159421.26
Authors	Smith, J.L.,Dodge, G.J. (deposition date: 2018-11-15, release date: 2019-03-13, Last modification date: 2023-10-11)
Primary citation	Dodge, G.J.,Patel, A.,Jaremko, K.L.,McCammon, J.A.,Smith, J.L.,Burkart, M.D. Structural and dynamical rationale for fatty acid unsaturation inEscherichia coli. Proc. Natl. Acad. Sci. U.S.A., 116:6775-6783, 2019 Cited by PubMed: 30872475 DOI: 10.1073/pnas.1818686116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation