6N13

UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin

Summary for 6N13

• Entry DOI: 10.2210/pdb6n13/pdb
• Related: 1UBQ 4Q5E 5N2W
• NMR Information: BMRB: 27664
• Descriptor: E3 ubiquitin-protein ligase parkin, ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (5 entities in total)
• Functional Keywords: e3 enzyme, protein degradation, mitochondrial protein, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 71885.83

Authors

Condos, T.E.C.,Dunkerley, K.M.,Freeman, E.A.,Barber, K.R.,Aguirre, J.D.,Chaugule, V.K.,Xiao, Y.,Konermann, L.,Walden, H.,Shaw, G.S. (deposition date: 2018-11-08, release date: 2018-11-28, Last modification date: 2020-01-08)

• Primary citation: Condos, T.E.,Dunkerley, K.M.,Freeman, E.A.,Barber, K.R.,Aguirre, J.D.,Chaugule, V.K.,Xiao, Y.,Konermann, L.,Walden, H.,Shaw, G.S.; Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.; EMBO J., 37:-, 2018; PubMed: 30446597; DOI: 10.15252/embj.2018100014

Experimental method

SOLUTION NMR