6MVM

LasR LBD L130F:3OC14HSL complex

Summary for 6MVM

Entry DOI	10.2210/pdb6mvm/pdb
Descriptor	Transcriptional regulator LasR, 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide (3 entities in total)
Functional Keywords	transcriptional activator protein, 3-oxo-n-(2-oxooxolan-3-yl)tetradecanamide, transcription
Biological source	Pseudomonas aeruginosa (strain UCBPP-PA14)
Total number of polymer chains	2
Total formula weight	37091.92
Authors	Paczkowski, J.E.,Bassler, B.L. (deposition date: 2018-10-26, release date: 2019-01-16, Last modification date: 2023-10-11)
Primary citation	Paczkowski, J.E.,McCready, A.R.,Cong, J.P.,Li, Z.,Jeffrey, P.D.,Smith, C.D.,Henke, B.R.,Hughson, F.M.,Bassler, B.L. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14:378-389, 2019 Cited by PubMed: 30763066 DOI: 10.1021/acschembio.8b00971 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.895 Å)

Structure validation