6MV1

2.15A resolution structure of the CS-b5R domains of human Ncb5or (NAD+ form)

Summary for 6MV1

Entry DOI	10.2210/pdb6mv1/pdb
Descriptor	Cytochrome b5 reductase 4, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	ncb5or, electron transfer, redox, heme, endoplasmic reticulum, fad, flavoprotein, iron, metal-binding, nad, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	43568.48
Authors	Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Benson, D.R.,Cooper, A.,Gao, P.,Zhu, H. (deposition date: 2018-10-24, release date: 2019-07-17, Last modification date: 2023-10-11)
Primary citation	Benson, D.R.,Lovell, S.,Mehzabeen, N.,Galeva, N.,Cooper, A.,Gao, P.,Battaile, K.P.,Zhu, H. Crystal structures of the naturally fused CS and cytochrome b5reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+nicotinamide ring. Acta Crystallogr D Struct Biol, 75:628-638, 2019 Cited by PubMed: 31282472 DOI: 10.1107/S205979831900754X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation