6MTW

Lysosomal Phospholipase A2 in complex with Zinc

Summary for 6MTW

Entry DOI	10.2210/pdb6mtw/pdb
Descriptor	Group XV phospholipase A2, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	lipase, esterase, hydrolase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	87721.06
Authors	Bouley, R.,Tesmer, J.J.G. (deposition date: 2018-10-22, release date: 2019-03-20, Last modification date: 2023-10-11)
Primary citation	Bouley, R.A.,Hinkovska-Galcheva, V.,Shayman, J.A.,Tesmer, J.J.G. Structural Basis of Lysosomal Phospholipase A2Inhibition by Zn2. Biochemistry, 58:1709-1717, 2019 Cited by PubMed: 30830753 DOI: 10.1021/acs.biochem.8b01124 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.999 Å)

Structure validation