Crystal structure of human Scribble PDZ1:pMCC complex

Summary for 6MTU

DescriptorProtein scribble homolog, Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, ... (7 entities in total)
Functional Keywordscell polarity, mcc, pdz domain, phosphorylation, cell adhesion
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight28104.29
Caria, S.,Stewart, B.Z.,Humbert, P.O.,Kvansakul, M. (deposition date: 2018-10-22, release date: 2019-08-14)
Primary citation
Caria, S.,Stewart, B.Z.,Jin, R.,Smith, B.J.,Humbert, P.O.,Kvansakul, M.
Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 2019
PubMed: 31317644 (PDB entries with the same primary citation)
DOI: 10.1111/febs.15002
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25730 1.9% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution