Crystal Structure of HLA-B*18:01 in complex with NP338 influenza peptide

Summary for 6MT3

DescriptorHLA class I histocompatibility antigen, B-18 alpha chain, NP338 peptide, Beta-2-microglobulin, ... (4 entities in total)
Functional Keywordstcr, t cell, influenza, hla, hla-b18, hla-b37, hla-b44, viral mutation, cd8 t cells, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains3
Total molecular weight44753.53
Gras, S. (deposition date: 2018-10-19, release date: 2019-02-13)
Primary citation
Grant, E.J.,Josephs, T.M.,Loh, L.,Clemens, E.B.,Sant, S.,Bharadwaj, M.,Chen, W.,Rossjohn, J.,Gras, S.,Kedzierska, K.
Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9:5427-5427, 2018
PubMed: 30575715 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-07815-5
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21830 0.3% 5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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