6MNR

Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide

Summary for 6MNR

• Entry DOI: 10.2210/pdb6mnr/pdb
• Descriptor: Envelope glycoprotein, Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, ... (6 entities in total)
• Functional Keywords: hiv-1 gp120 v3 antibody, immune system
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 3
• Total formula weight: 49576.97

Authors

Nicely, N.I. (deposition date: 2018-10-02, release date: 2019-07-24, Last modification date: 2023-10-11)

• Primary citation: Han, Q.,Jones, J.A.,Nicely, N.I.,Reed, R.K.,Shen, X.,Mansouri, K.,Louder, M.,Trama, A.M.,Alam, S.M.,Edwards, R.J.,Bonsignori, M.,Tomaras, G.D.,Korber, B.,Montefiori, D.C.,Mascola, J.R.,Seaman, M.S.,Haynes, B.F.,Saunders, K.O.; Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.; Nat Commun, 10:2898-2898, 2019; PubMed: 31263112; DOI: 10.1038/s41467-019-10899-2

Experimental method

X-RAY DIFFRACTION (2.201 Å)