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6MJI

Crystal structure of the mCD1d/xxs (JJ304) /iNKTCR ternary complex

Summary for 6MJI
Entry DOI10.2210/pdb6mji/pdb
DescriptorT cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, N-[(2S,3S,4R)-1-{[4-O-(cyclopropylmethyl)-alpha-D-galactopyranosyl]oxy}-3,4-dihydroxyoctadecan-2-yl]hexacosanamide, Beta-chain,Tcell receptor chain,T cell receptor beta constant 2, ... (11 entities in total)
Functional Keywordsmhc-fold, ig-fold, glycolipid antigen presentation, t cell receptor, immune system
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains4
Total formula weight97427.03
Authors
Zajonc, D.M.,Bitra, A.,Janssens, J. (deposition date: 2018-09-20, release date: 2019-01-09, Last modification date: 2023-10-11)
Primary citationJanssens, J.,Bitra, A.,Wang, J.,Decruy, T.,Venken, K.,van der Eycken, J.,Elewaut, D.,Zajonc, D.M.,van Calenbergh, S.
4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14:147-168, 2019
Cited by
PubMed: 30556652
DOI: 10.1002/cmdc.201800649
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

건을2024-03-27부터공개중

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